Re: WSN: free energies calculstions (fwd)

• To: Water Science Network <water@gibbs.oit.unc.edu>
• Subject: Re: WSN: free energies calculstions (fwd)
• From: Water Science Network Administrator <wsn-adm@mmlds1.pha.unc.edu>
• Date: Mon, 28 Nov 1994 19:12:19 -0500 (EST)

Sender: KAHN@mbcl.rutgers.edu
Subject: Re: WSN: free energies calculstions


The classic paper on free energies of amino acid transfer between water
and nonaqueous solution is by Nozaki & Tanford, J. Biol. Chem. 246: 2211-
2217 (1971).  The free energies of transfer were shown to be linear in the
solvent accessible surface area by Chothia, Nature 248: 338-339, 1974.
The linearity with surface area of transfer free energies was shown for
many compounds earlier by Heremans.  See the review by F. M. Richards
in Annual Review of Biophysics & Bioengineering, vol. 6, 1977.  I believe the
page to be 151, but of that I'm not sure.

These should give you a start that's relatively digestible.  There has been
quite a bit of work since, and there are some controversies.  What do you
plan to do with all this?

Peter Kahn

• Prev: WSN: free energy of folding, contact energies (fwd)
• Next: Experimental results - Ions and Solvent around polymers and biomolecules (fwd)
• Index: Mail Index
• Thread: Mail Thread Index